Mar 19-20, 2020    London, UK

World summit on Microbes and Yeast Research


Fungal physiology is a logical instruction that worries the life-supporting capacities and procedures of fungi that enables fungal entities to develop and replicate.

  • Glucose Waste Water Life Cycle Water Management Water Pollution

The great intensity of yeast genetics is mostly because of the capacity to rapidly outline phenotype-generating quality to a region of the S. cerevisiae genome. S. cerevisiae stood as the ideal system for ample of molecular genetic research for the past 20 years as the simple cellular mechanisms of replication, recombination, cell division and metabolism are usually preserved among yeast and larger eukaryotes, along with mammals. The field of biology and genetics that studies the structure and function of genes at a molecular level is Molecular genetics. The study of gene expression and chromosomes of an organism can give awareness of heredity, genetic variation, and mutations. For the study of cellular events, yeast provides a flexible and rapid genetic system. Just after 2d of growth, colonies containing millions of cells are been produced. Moreover, in both haploid and diploid forms, yeast can propagate, greatly easing genetic analysis. Like bacteria, haploid yeast cells can be changed to create particular nourishing prerequisites or auxotrophic hereditary phenotypes, and latent deadly transformations can either be kept up in haploids as contingent deadly alleles (e.g., temperature-touchy mutants), or in heterozygotic diploids, which carry both wild-type and mutant alleles.

  • Regulation of gene expression RNA processing and regulation Yeast biotechnology Yeast genomics Yeast stress response

In yeast aging is measured by the number of divisions an individual cell completes before it dies but not by the time. Yeast divides asymmetrically by budding off as new daughters so it is easy to follow from birth to death. Compared to their mothers the daughters actually have full lifespan. Thus explains that the yeast population is immortal and the individual cells are mortal. As the number of divisions increases the probability of a cell to divide decreases. Thus rate of mortality increases with age. Similar to other species yeast also plateaus when they become older. Some deter mental changes are seen in Yeast when they age. Practically the lifespan of yeast is measured by periodically observing cells under a microscope and removing buds with the help of micro-manipulator. To eliminate dangerous, superfluous, or damaged cells, “Apoptosis” is an evolutionally conserved cell suicide program used by an organism. The occurrence of yeast cells experiencing apoptosis has long been contentious partly since the doubts of whether cell suicide may possibly constitute developmental benefits for unicellular organisms.

  • Cell immortality Cell immortalization Cellular immortality Cytogerontology Hayflick phenomenon

The study of the mechanisms of heritable information in fungi is fungal genetics. For eukaryotic genetic research, comprising cell cycle regulation, chromatin structure, genetic recombination and gene regulation, yeasts and filamentous fungi are largely used as model organisms.

  • Fungi Genetics Mating type Mitochondria Tetrads

To make beer and wine from grains and fruits, humans have taken advantage of the metabolism in a tiny fungus. Yeast biotechnology is defined as the application of yeast to the development of industrial products and processes. In various fields such as bread making, wine brewing, chocolate production, probiotics, etc. fermentation is being used.

  • Saccharomyces cerevisiae Non-Saccharomyces yeasts Fermentation-derived products Wine Beer

In large scale screenings, the humanized yeast model has emerged as a powerful tool to target human proteins. The high degree of cellular processes preservation among the yeast Saccharomyces cerevisiae and higher eukaryotes has made this microorganism a valuable cell model to study the pathobiology of several human diseases. Screening of potentially active compounds in the first line to be tested in more complex cell models, the yeast target based approach can be highly useful.

  • Yeast Drug discovery Pharmaceutical industry High-throughput screening Proteome

Yeast can be used for bioremediation or biodegradation of contaminants and hazardous pollutants in the environment. Due to industrialisation and human interfacing on limited natural resources, the environment is under great stress. Bioremediation is a process of cleaning up a polluted site to consume or break down environmental pollutants with the use of either naturally occurring or deliberately introduced microorganisms or other forms of life. Bioremediation is based on bio-degradative process related to microbial population dynamics in soil or water and its ability to consume xenobiotic as a carbon source.

  • Bioremediation Petroleum Limiting factors Alkanes Cytochrome P450

Nourishment deterioration because of bacteria or yeast sullying can be an expensive issue for the food industry. New advancement in DNA study has empowered quick, precise yeast recognizable proof techniques to be created. Equipped with this exactness identification it is likely to anticipate and remove the basis of contaminating. Some yeast can grow at relatively low temperatures they are psychrophilic. Indeed, the fermentation of wine and beer is frequently carried out at temperature near 40°F. Since certain classes are psychrophiles, they can produce a spoilage problem in meat coolers and other refrigerated storage areas. As they can develop under circumstances of high salt or sugar content, they can cause the decay of certain foods in which bacteria would not grow. Nutrition made by the bacterial fermentation process, such as pickles and sauerkraut, can also be ruined by yeasts which interfere with the regular fermentative process. Even though some yeasts are pathogenic, yeast infections are much less common than bacterial infections. Foodborne disease keeps on being an urgent issue over the globe. The study of disease transmission of the foodborne disease is evolving. New pathogens have developed, and some have spread around the world. These pathogens cause a huge number of instances of sporadic illness and chronic diseases, and challenging outbreaks over many states and nations.

  • Lactic Acid Bacterium Food Poisoning Clostridium Botulinum Food Preservative Food Microbiology

Most yeast infections are occurred by a category of yeast called Candida albicans. Yeast is a fungus that usually lives in the vagina in small numbers. A vaginal yeast infection means that too many yeast cells are rising in the vagina. These infections are very usual. When something happens to change the equilibrium of these organisms, yeast can grow too much and cause signs. Vaginal yeast toxicities aren’t considered a sexually transmitted infection (STI). Sexual contact can spread it, but women who aren’t sexually active can also get them. Once you get a yeast infection, you’re also more possible to get another one. Enzymes involved in lipid metabolism were indeed found to play a major role in cancer cell proliferation, and most of these enzymes are conserved in the yeast, Saccharomyces cerevisiae. Most notably, cancer cell physiology and metabolic fluxes are very similar to those in the fermenting and rapidly proliferating yeast.

  • Rare yeast Immunocompromised hosts Fungemia Intravascular catheter-associated infections Trichosporon

Nuclear RNA handling requires dynamic and intricately regulated machinery generated of multiple enzymes and their cofactors. Much improvement has been made recently in defining the 3D structure of many elements of the nuclear deprivation machinery and its cofactors. Likewise, the regulatory mechanisms that administer RNA processing are steadily coming into focus. Such improvements invariably generate many new queries, which we spotlight in this Yeast Congress 2018.

  • Cryptic unstable transcript Exosome Mtr4p Polyadenylation Small nuclear RNA

Lipids gained much attention due their involvement in health and disease, during last decades. Lipids contribute too many different processes such as energy supply; cell signalling and cell death and they are required for the formation of membranes. In lipid metabolism, different organelles, like endoplasmic reticulum, mitochondria, peroxisomes and lipid droplets are involved in lipid metabolism. To study biochemistry, molecular biology and cell biology of lipids, yeast saccharomyces cerevisiae has become a reliable model organism. The availability of mutants bearing defects in lipid metabolic pathways and the ease of manipulation by culture conditions facilitated these investigations.

  • Saccharomyces cerevisiae, fatty acids, phospholipids, sphingolipids, sterols, triacylglycerols

At the beginning stage of the manufacturing process, strain purity and trueness to type are carefully controlled. In the laboratory, a pure culture of the yeast strain being used is maintained and prepared for inoculation into the initial fermentation vessel. Strict adherence to sanitary practices and GMPrules of the Food and Drug Administration are required at all stages of yeast production to produce products with acceptable microbiological standards. Complete microbiological testing is conducted on all finished yeast product using approved and published methods. This insures product safety and lack of potentially harmful organisms. Dakota Baker’s Yeast microbiological standards have Salmonella sp. specification of negative/375 grams and an E.coli specification of less than 100/gram.

Soil microorganisms are the most abundant of all the biota in soil and responsible for driving nutrient and organic matter cycling, soil fertility, soil restoration, plant health and ecosystem primary production. Beneficial microorganisms include those that create symbiotic associations with plant roots (rhizobia, mycorrhizal fungi, actinomycetes, diazotrophic bacteria), promote nutrient mineralization and availability, produce plant growth hormones, and are antagonists of plant pests, parasites or diseases (biocontrol agents). Many of these organisms are already naturally present in the soil, although in some situations it may be beneficial to increase their populations by either inoculation or by applying various agricultural management techniques that enhance their abundance and activity. Rhizobia Biocontrol fungi Growth Promoting Bacteria Nitrogen (N2) Fixing Bacteria Impact of microorganisms on plant growth and health Plant-microbe interactions in a changing world

Microbiology is the study of microscopic organisms, such as bacteria, viruses, archaea, fungi, and protozoa. It includes fundamental research on the biochemistry, physiology, cell biology, ecology, evolution and clinical aspects of microorganisms, including the host response to these agents

Women play an undeniable role in the health of future generations partly through the maternal microbes. The microbial inheritance that occurs pre-, peri-, and post-natal has been linked to various consequences for both mother and child.

Bacterial diseases refer to a large variety of diseases caused by bacteria or bacterial components that affect humans, domesticated animals, wildlife, fish, and birds. Most of these diseases are contagious—that is, they can be passed from one member of a species to another member, or, in a smaller number of instances, from one species to a different species. Depending on the organism, bacterial disease can be spread in different ways. Contagiousness | Respiratory | Gastrointestinal | Exanthematous Hepatic | Transmission | Cutaneous | Transmission | Hemorrhagic Neurologic | Transmission | Bottom line

Microorganisms includes all the microbes can be processed in such a way that it can be utilized in a healthy product.There are many useful application of microbes in the food and Dairy industry. They influence the quality, availability and quantity of food. Microorganisms are used to change one substance to another which is used as food, such as milk to yoghurt and cheese, sugar to wine, bread, probiotics and dietary fibers, preparation of antibiotics such as penicillin, streptomycin.

A few harmful microbes, for example less than 1% of bacteria, can invade our body (the host) and make us ill. Microbes cause infectious diseases such as flu and measles.There is also strong evidence that microbes may contribute to many non–infectious chronic diseases such as some forms of cancer and coronary heart disease. Different diseases are caused by different types of micro-organisms. Microbes that cause disease are called pathogens.

A microbiome is the community of microorganisms such as bacteria, archaea, fungi, as well as viruses that inhabit an ecosystem or organism. Microorganisms dominate all other life everywhere scientists have looked, including the human body, the Earth’s soils and sediments, the oceans and fresh waterways, the atmosphere and even extreme environments such as hydrothermal vents and subglacial lakes. Scientists also use the term microbiome to refer to all these genes associated with those life forms. The Earth Microbiome The Ocean Microbiome The Animal Microbiome Modulation of Microbiota The Human Microbiome The Atmospheric Microbiome

Marine microbiology is the study of microorganisms and non-organismic microbes that exist in saltwater environments, including the open ocean, coastal waters, estuaries, on marine surfaces and in sediments. Aquatic microbiology is the science that deals with microscopic living organisms in fresh or salt water systems. Aquaculture & Marine Biotechnology helps to control the marine organisms and water borne organisms. It is a process which has to do with marine or underwater environment. Blue Biotechnology is used to protect the marine organisms from harmful diseases underwater. The control of seasonal production and reproduction in farm animals has become major research goals. The applications of biotechnology to fish farming and ornamental fish production are numerous and valuable in both economic (food production, aquarium trade) and environmental terms (conservation of natural biodiversity for endangered species and protection of natural biodiversity from escapee domesticated strains). With the growing demand for fish products, biotechnology can help in the development of high quality, economical produce, thereby reducing pressure on natural population. Applications of Marine Biotechnology Marine Microbiology and Biodiversity Biotechnology applications to Aquaculture Marine-based Drug Discovery and Development Environmental Risk of Aquatic Organisms from Genetic Biotechnology

The gut microbiome is made up of billions of bacteria and other microorganisms that co-exist with other human cells in the lower intestine.It helps with digestion, metabolism, immune function and brain health.Our gut microbiome begins to develop in very early life, and is influenced by genetics, delivery method, age, stress, illness, environment, medication use, and diet.