Sessions

Jun 29-30, 2021    Paris, France

International Conference on Genetic Engineering and Gene Therapy

Sessions

Genome editing (also called gene editing) is a group of technologies that give scientists the ability to change an organism's DNA. These technologies allow genetic material to be added, removed, or altered at particular locations in the genome. However gene therapy is an experimental technique that uses genes to treat or prevent disease. In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.

CRISPR (clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found within the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments from viruses that have previously infected the prokaryote and are used to detect and destroy DNA from similar viruses during subsequent infections. Hence these sequences play a key role in the antiviral defence system of prokaryote. Cas9 (or "CRISPR-associated protein 9") is an enzyme that uses CRISPR sequences as a guide to recognize and cleave specific strands of DNA that are complementary to the CRISPR sequence. Cas9 enzymes together with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within organisms. This editing process has a wide variety of applications including basic biological research, development of biotechnology products, and treatment of diseases.

Artificial intelligence could very well be the future of biotechnology, and it has become a crucial part of life sciences. Artificial intelligence is now making headway into biotech and such related industries, but it is not the only one making progress and bringing change. Artificial intelligence has made some exciting improvements to medicine, and biotech companies and pharmaceutical companies are employing artificial intelligence in drug discovery with a lot of positive results.

  • Introduction to Artificial Intelligence
  • AI in clinical diagnosis
  • Artificial Neural network as a Biotech tool

Adipose tissue stem cells (ASCs), known as multipotent stem cells, are most commonly used in the clinical applications in recent years. Adipose tissues (AT) have the advantage in the harvesting, isolation, and expansion of ASCs, especially an abundant amount of stem cells compared to bone marrow. ASCs can be found in stromal vascular fractions (SVF) which are easily obtained from the dissociation of adipose tissue.

Microbial/Industrial biotechnology is the use of biotechnology for modern capacities, together with modern aging. The observation of exploited cells like microorganisms, or components of cells like compounds, to think of mechanically supportive item in segments like synthetic concoctions, nourishment and feed, cleansers, paper and mash, materials and biofuels. Modern Biotechnology offers a head discussion crossing over essential investigation and R&D with later-arrange advancement for supportable bio base for the most part of industrial and ecological applications.

Agricultural biotechnology is a pile of tools, containing traditional breeding methods that alter living organisms, or parts of organisms, to make or modify products, improve plants or animals for specific agricultural uses. Plant Biotechnology is a set of techniques used to adapt plants for specific needs or opportunities. Plant Biotechnology applies technological methods to biological organisms. Plant biotechnology can be defined as the introduction of desirable traits into plants through genetic modification.

  •  Organic Farming
  • Livestock Farming and Production
  • Plant Functional Biology and Biotechnology
  • Plant Pathology and Immunology
  • Plant Micropropagation

Genetic engineering technology offers great potential to reduce the costs of producing cellulosic ethanol. ... Finally, future research on the upregulation of cellulose and hemicellulose biosynthesis pathway enzymes for increased polysaccharides will also have the potential to increase cellulosic biofuel production.

Genetic Engineering, also called recombinant DNA technology, involves the group of techniques used to cut up and join together genetic material, especially DNA from different biological species, and to introduce the resulting hybrid DNA into an organism in order to form new combinations of heritable genetic material. Genetic engineering has been applied in numerous fields including research, medicine, industrial biotechnology and agriculture. Many more new discoveries are invented in the Genetic Research. But the few Recent Discoveries in Genetic Engineering.

1.            GM Mosquito Progeny Not Dying in Brazil: Study:

2.            Timing and Order of Molecular Events Recorded in Live Cells’ DNA

3.            FDA Lifts Import Restrictions on Genetically Engineered Salmon

4.            Gene Drive–Equipped Mosquitoes Released into Lab Environment

5.            Better Base Editing in Plants

6.            Info graphic: Plant Genome Editors Get A New Tool

7.            Opinion: GE Crops Are Seen Through a Warped Lens

Nano Biotechnology is a discipline wherein tools from nanotechnology are created and connected to think about organic marvels. Nano biotechnology, bio nanotechnology, and Nano science are terms that allude to the crossing point of nanotechnology and science. Bio nanotechnology and Nano biotechnology fill in as cover terms for different related advancements. The most significant goals that are habitually found in Nano science include applying Nano instruments to important restorative/natural issues and refining these applications. Growing new instruments, for example, peptide Nano sheets, for medicinal and organic designs is another essential target in nanotechnology.

  • Nanomaterial science
  • Advances in Nano science and Nano technology
  • Future potential of Nano technology

Pharmaceutical Biotechnology is the science that covers all innovations required for creating, assembling and enrollment of organic medications. Pharmaceutical organizations use biotechnology for assembling drugs, pharmacogenomics, quality treatment, and hereditary testing. Biotech organizations make biotechnology items by controlling and adjusting living beings, more often than not at atomic level. Pharmaceutical Biotechnology is an undeniably significant region of science and innovation. It contributes in plan and conveyance of new helpful medications, demonstrative specialists for therapeutic tests, and in quality treatment for revising the restorative side effects of genetic maladies. The Pharmaceutical Biotechnology is broadly spread, running from numerous moral issues to changes in medicinal services rehearses and a noteworthy commitment to the improvement of national economy. Euro Biotechnology 2020 will concentrate on Biopharmaceuticals Discovery, Biopharmaceutical Regulations and Validations, Biologics and Biosimilars and Clinical Research/Clinical preliminaries.

Animal research:

Animal Genetics analyzes the heredity and varieties in animals. Animals have an autonomous legacy of characters due to their generous number of chromosomes. Half breed Analysis is the key strategy to consider the legacy of characters and it picks the possibility of different morphological, physiological and biochemical characteristics which a huge piece of the time depend just on one of a few arrangements of characteristics.

Human research:

Human genetics, is study for Analysis of the parent's succession of characteristics. In human heritage as no fundamental way differs from that in other organisms. Human heredity research occupies a key genetic role. Much of this fascination derives from a deep desire to know who and why human beings are as they are. In a more practical way, Understanding human inheritance is critical in the prediction, diagnosis and treatment of genetic diseases. The quest to establish human health's genetic basis has given rise to the medical genetics industry. Medicine has generally given emphasis and purpose to human genetics, so it is often considered interchangeable with the terms of clinical genetics and human genetics.

DNA Sequencing is the process of determining the actual order of nucleotide (Adenine, Guanine, Cytosine, and thymine) within a DNA molecule. This technique is used in various fields such as medical diagnosis, biotechnology, forensic biology, virology, and biological systematics and anthropology.

  1. Shotgun Sequencing
  2. Bridge PCR
  1. Massively Parallel Signature Sequencing (MPSS)
  2. Polony Sequencing
  3. 454 Pyrosequencing
  4. llumina (Solexa) Sequencing
  5. Solid Sequencing
  6. Ion Torrent Semiconductor Sequencing, DNA Nanoball Sequencing
  7. Heliscope Single Molecule Sequencing
  8. Single Molecule Real Time (SMRT) Sequencing
  9. Nanopore DNA Sequencing

Genetic Counselling is the procedure by which the patients or relatives at risk of an acquired disorder are advised with the outcomes and nature of the disorder, the likelihood of creating or transmitting it, and the choices open to them in management and family planning. This mind boggling procedure can be isolated into indicative and supportive aspects. The most surely understood sort of value transport is as DNA that encodes the common sense helpful quality to supplant the target changed quality. The polymer particles are packaged inside a vector which passes on the iotas inside and helps in their compromise. Gene Therapy is an exceptionally viable however simple to disprove sort of treatment of inherited issue dependent upon their level of sensibility and social and good affirmation.

Genes are the structure squares of heredity. They are passed from parent to tyke. They hold DNA, the directions for making proteins. Proteins do the vast majority of the work in cells. They move particles starting with one spot then onto the next, form structures, separate poisons, and do numerous other support employments.

At times there is a transformation, an adjustment in a quality or genes. The transformation changes the quality's guidelines for making a protein, so the protein does not work appropriately or is missing totally. This can cause an ailment called a hereditary issue.

You can acquire a quality change from one or the two guardians. A transformation can likewise occur amid your lifetime.

There are a number of different types of genetic disorders (inherited), including the following:

•           Single gene inheritance

•           Multifactorial inheritance

•           Chromosome abnormalities

•           Mitochondrial inheritance

Immunogenetics is the branch of medical research that explores the relationship between the immune system and genetics. Autoimmune diseases, such as type 1 diabetes, are complex genetic traits which result from defects in the immune system. Identification of genes defining the immune defects may identify new target genes for therapeutic approaches. Alternatively, genetic variations can also help to define the immunological pathway leading to disease.

  • The immunogenetics of Neurological Disease
  • Immune-suppressive effects of interleukin-6
  • Bone involvement in monogenic autoinflammatory syndromes
  • Immunoglobulin genotypes and cognitive functions
  • Mechanisms behind TB, HBV, and HIV chronic infections

Cancer genetics is that the study of genetic mutations liable for most cancers, the usage of genome sequencing and bioinformaticsMedical genetics is to boost cancer treatment and results lies in determinant that sets of genes and gene interactions have an effect on different subsets of cancers. International cancer genome consortium (ICGC) is a voluntary scientific organization that provides a forum for collaboration among the world's main cancer and genomic researchers. Cancer-causing genetic changes can also be acquired during one’s lifetime, as the result of errors that occur as cells divide or from exposure to carcinogenic substances that damage DNA, such as certain chemicals in tobacco smoke, and radiation, such as ultraviolet rays from the sun. Genetic changes that occur after conception are called somatic changes.

Molecular Biology is the field of biology that studies the composition, structure, and interactions of cellular molecules – such as nucleic acids and proteins that carry out the biological processes essential for the cell’s functions and maintenance.

Molecular biology also plays important role in understanding formations, actions, and regulations of various parts of cells which can be used to efficiently target new drugs, diagnose disease, and understand the physiology of the cell.

Like Biochemistry, Molecular Biology deals with the structure and function of proteins and how genes are expressed in cells. Genetics covers most of the same genetic parts of Molecular Biology and also includes a non-molecular part like evolutionary Genetics, population Genetics, etc

Epigenetics are stable heritable traits that cannot be explained by changes in DNA sequence. Epigenetics often refers to changes in a chromosome that affect gene activity and expression, but can also be used to describe any heritable phenotypic change that does not derive from a modification of the genome, such as prions. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal developmental program. Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA. These epigenetic changes may last through cell divisions for the duration of the cell's life, and may also last for multiple generations even though they do not involve changes in the underlying DNA sequence of the organism; instead, non-genetic factors cause the organism's genes to behave or "express themselves" differently.

  • Structure and Epigenetic Regulation of Chromatin Fibers
  • DNA methylation
  • X-inactivation
  • Histone modification
  • Basics of Epigenetic Control-Primer in Genetics and Genomics

Gene mapping describes the ways used to identify the locus of a gene and also the distances between genes. The essence of all genome mapping is to put a group of molecular markers onto their several positions at the genome. Molecular markers come in all forms. Genes can be viewed as one special style of genetic markers within the creation of genome maps and mapped the same way as other markers. Mapped features that are not genes are called DNA markers. As with gene markers, a DNA marker must have at least two alleles to be useful. There are three types of DNA sequence feature that satisfy this requirement: restriction fragment length polymorphisms (RFLPs)simple sequence length polymorphisms (SSLPs), and single nucleotide polymorphisms (SNPs).

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