Longdom Conferences

Scientific program

Jun 14-15, 2027    Barcelona, Spain
4th International Conference on

Pharmaceutics and Advanced Drug Delivery Systems

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Coffee may help the body fight stress and aging through a hidden cellular switch

2026-07-19 - 2026-07

Scientists may have uncovered one reason coffee is repeatedly associated with healthier aging and lower disease risk. Compounds in coffee appear to activate NR4A1, a receptor that helps protect cells from stress, inflammation, and damage. These protective effects disappeared when the receptor was removed, strengthening the connection. Surprisingly, plant-based compounds such as caffeic acid seemed far more active than caffeine itself.

Scientists tested 39 sweeteners and found unexpected gut effects

2026-07-17 - 2026-07

A large laboratory study found that many commonly used sweeteners can directly change the growth of gut bacteria. Researchers identified more than 100 cases in which sweeteners behaved differently when combined with medications, caffeine, or flavorings. The combination of isosteviol and the antidepressant duloxetine was especially disruptive, reducing beneficial bacteria and overall microbial diversity.

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