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Scientists uncover a new role for blood-brain barrier in neuron function and damage

2022-12-29 - 2022-12

Researchers have made a surprising discovery linking Delta/Notch signaling in subperineurial glia (SPG) to the regulation of nerve ensheathment and neurotransmitter release at the Drosophila neuromuscular junction (NMJ). SPG, the counterpart of the endothelial layer in the vertebrate blood-brain barrier, form the key cellular layer that is critical for axonal ensheathment and the blood-brain barrier in Drosophila. The results provide a mechanistic insight into the biology of barrier function and glia-neuron interactions.

Researchers have made a surprising discovery linking Delta/Notch signaling in subperineurial glia (SPG) to the regulation of nerve ensheathment and neurotransmitter release at the Drosophila neuromuscular junction (NMJ). SPG, the counterpart of the endoth

2022-12-29 - 2022-12

Researchers at the University of California, Irvine are conducting pioneering research into the concept that unpredictable parental behaviors, together with unpredictable environment, such as lack of routines and frequent disasters, disrupt optimal emotional brain circuit development in children, increasing their vulnerability to mental illness and substance abuse.

Interactions between genetics and the environment can explain variability seen in common neuropsychiatric disorders

2022-12-29 - 2022-12

While some diseases and disorders can be easily attributed to specific genetic mutations, for many diseases -- especially neuropsychiatric ones -- the causes are much more complicated, influenced by both genetic and environmental factors. A new study at the University of Chicago examined data from over 400,000 individuals to better understand how those two factors play into the variations seen in a number of neuropsychiatric disorders, with the hope of eventually identifying ways that individuals who are at risk can modify their environments to protect their mental health. The research was published on September 6 in Cell Reports Medicine.

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Scientists uncover a new role for blood-brain barrier in neuron function and damage

Researchers have made a surprising discovery linking Delta/Notch signaling in subperineurial glia (SPG) to the regulation of nerve ensheathment and neurotransmitter release at the Drosophila neuromuscular junction (NMJ). SPG, the counterpart of the endoth

Interactions between genetics and the environment can explain variability seen in common neuropsychiatric disorders

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Clinical Psychiatry and Mental Health

Scientists uncover a new role for blood-brain barrier in neuron function and damage

Researchers have made a surprising discovery linking Delta/Notch signaling in subperineurial glia (SPG) to the regulation of nerve ensheathment and neurotransmitter release at the Drosophila neuromuscular junction (NMJ). SPG, the counterpart of the endoth

Interactions between genetics and the environment can explain variability seen in common neuropsychiatric disorders