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Analytical methods including chromatographic methods are commonly used for the quantitative and qualitative analysis of raw materials, drug substances, drug products, and compounds in biological samples in the pharmaceutical industry. The components monitored include chiral or achiral drugs, process impurities, residual solvents, excipients such as preservatives, degradation products, extractable and leachable from container and closure or manufacturing process, pesticide in drug product from plant origin, and metabolites.
Biopharmaceutics is defined as the study of factors that influencing the rate and amount of drug which reaches the systemic circulation and the use of this information to optimize the therapeutic efficacy of the drug products. The process of movement of the drug from the site of administration to the systemic circulation is called absorption. The concentration of drug in plasma, onset of action, intensity and duration of response depend upon the bioavailability of drug from its dosage form
Pharmaceutical technology is the application of scientific knowledge or technology to pharmacy, pharmacology, and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures and in the treatment of patients. Pharma Technology Focus is now available on all devices
Smart Drug Delivery Systems (SDDS) have emerged as a panacea for many clinically useful drugs weighed down with toxicity. The discovery of Amphotericin B as a liposome has raised hopes and directed mammoth efforts in SDDS. The concept of manipulation of toxicity has given rise to additional significant approaches like targeting and use of Physico-chemical approaches. Currently the spectrum of SDDS comprises of targeting liposomes, drug-loaded biodegradable microspheres, stimuli-responsive
Applied pharmacology is the study of how drugs affect body. Drugs can be used to both maintain a healthy lifestyle and treat or cure disease. It also provides explanation for different drugs having connected with the pharmacological action. It gives clarifications about drug interactions and the action of various drugs on the many organs in the body when they are in diseased state with side effects contradictions.
- Molecular and cellular pharmacology
- Pharmacological testing
- Behavioral pharmacology
- Clinical application of systems pharmacology models
Biopharmaceutical informatics endeavours to use information technology, sequence-and structure-based bioinformatics analyses, molecular modelling and simulations, and statistical data analyse towards biologic drug development. Development of databases containing the experimental data on biophysical stability, safety along with molecular categorization.
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