Latest News for Fungal Infections and Treatments

2020-12-28

Scientists at St. Jude Children's Research Hospital have identified the mechanisms behind inflammasome activation driven by infection with the fungal pathogen Aspergillus fumigatus. A new study published in the journal Science of The Total Environment in November 2020 discusses this potentially serious issue along with its wider consequences. UC San Francisco scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hour. A new study published on the preprint server bioRxiv in November 2020 discusses the characteristics of COVID-19 associated pulmonary aspergillosis (CAPA). One New Year's Day, Rob Purdie woke up with a headache that wouldn't quit. Vision problems, body aches and a slight fever followed. At the emergency room, the Bakersfield, California, resident was given antibiotics, which didn't touch his symptoms. The pathogenic fungus Candida auris, which first surfaced in 2009, is proving challenging to control. It is resistant to many fungicides and not easy to diagnose. A new post-mortem study of patients who have died from COVID-19 found severe damage to the lungs and signs of blood clotting in major organs. Recent studies indicate HIV infection heightens the risk of dental cavities - but a Rutgers researcher has found evidence that the risk of cavities comes not from HIV itself but from a weakened immune system, which could be caused by other diseases. In the June 11 issue of the New England Journal of Medicine, a team of UCLA physicians and scientists describes the first case of immune modulation being used to cure a severe and often fatal fungal infection. With many hundreds of thousands of deaths due to the current COVID-19 pandemic, there is a rush to find an effective vaccine or drug against the virus. A new study on the preprint server medRxiv* in May 2020 shows that the use of some biologically plausible drugs may be counterproductive, and care should be taken when trying out unproven therapies. There are many fungi that live in the body that make up the normal body microbial flora. One type, Candida, a type of yeast, normally thrives in small amounts in areas such as the skin, abdomen, and mouth, without causing any problem. But, when the body’s environment is altered, the yeast can uncontrollably proliferate and cause disease.

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