Title: Critical Evaluation of Neuro-protective Drugs in Ayurveda

Abstract:

Plant secondary metabolites include an array of bioactive constituents form both medicinal and food plants able to improve human health. The exposure to those phytochemicals, including phenylpropanoids, isoprenoids and alkaloids, through correct dietary habits, may promote health benefits, protecting against the chronic degenerative disorders mainly seen in Western industrialized countries, like cancer, cardiovascular and neurodegenerative diseases. During this review, I briefly cope with some plant foods and herbs of traditional medicines and diets that specialize in their neuroprotective active components. Because oxidative stress and neuro-inflammation resulting from neuroglial activation, at the amount of neurons, microglial cells and astrocytes, are key factors within the etiopathogenesis of both neurodegenerative and neurological diseases, emphasis are going to be placed on the antioxidant and antiinflammatory activity exerted by specific molecules present in food plants or in remedies prescribed by herbal medicines. Neuroprotection refers to the strategies and relative mechanisms able to defend the central nervous system (CNS) against neuronal injury due to both acute (e.g. stroke or trauma) and chronic neurodegenerative disorders (e.g. Alzheimer's disease, AD, and Parkinson's disease, PD). Among these strategies, herbal medicine may represent a valuable resource in prevention rather than in therapy of some CNS diseases, in association with a healthy lifestyle including correct dietary habits and moderate physical activity. As complementary and alternative therapy, herbal medicine, or simply phyto-therapy, refers to the medical use of plant organs (leaves, stems, roots, flowers, fruits and seeds) for their curative properties. Generally, herbal products contain complex mixtures of active components, including phenylpropanoids, isoprenoids and alkaloids, and it is often difficult to determine which components of the herbs has biological activity.

Biography:

Dr. Sunil Pal has completed his B.A.M.S Graduation at the age of 24 years from Rajiv Gandhi University of Health Sciences (Bangalore), India. He is now pursuing Post graduation in M.D. Kayachikitsa (Internal Medicine- Ayurveda) from Maharashtra University of Health Sciences (Nashik), India. He has over 9 International Publications with 2 Abstract as titled in souvenir in his Post graduation academics period. Recently he has been awarded with “Bharat Gaurav Puraskar 2021” and “Certificate of Excellence” for outstanding contribution in the field of “Ayurveda Physician”. Recently nominated as “Young Scientist” by VDGOOD Foundation, Coimbatore & Also nominated as “National Excellency Award” by KTK Foundation, New Delhi. He has won many prizes in Quizzes, Paper presentations, Poster presentations, Essay writings, Article writings etc. He is active member of N.Y.L.P. NGO, Mumbai, India also Supporting Member of AAPNA (Association of Ayurvedic Professionals of North America, USA). He is currently doing research trial on Gokshura (Tribulus terrestris) herbs in Stage-I Hypertension. He is determined to pursue Academia Research. He is enamored of teaching and Clinical Research. He has main interest in Blood disorders, Neurology Auto-immune disorders, Oncology, Nephrology in Ayurveda.