The chemical controlling life and death in hair follicles

2022-08-08 - 2022-08

A single chemical is a key to controlling when hair follicle cells divide, and when they die. This discovery could not only treat baldness but ultimately speed up wound healing because follicles are a source of stem cells. Most cells in the human body have a specific form and function determined during embryonic development that does not change. For example, a blood cell cannot turn into a nerve cell, or vice versa. Stem cells, however, are like the blank tiles in a game of Scrabble; they can turn into other types of cells.

New stem cell mechanism in your gut

2022-08-08 - 2022-08

Stem cells are a hot topic for creating medical treatments. However, scientists still do not fully understand how they choose to divide or differentiate to renew organs. Researchers have now found a new biophysical mechanism that regulates stem cells in the intestines of mice. There, a stem cell is not purely defined by intrinsic molecular markers but also by their location and movements in their environment. This could have implications for possible new treatments.

New patent-pending method mass-produces antitumor cells to treat blood diseases and cancer

2022-08-08 - 2022-08

A Purdue University chemical engineer has improved upon traditional methods to produce off-the-shelf human immune cells that show strong antitumor activity, according to a paper published in the peer-reviewed journal Cell Reports. Xiaoping Bao, a Purdue University assistant professor from the Davidson School of Chemical Engineering, said CAR-neutrophils, or chimeric antigen receptor neutrophils, and engraftable HSCs, or hematopoietic stem cells, are effective types of therapies for blood diseases and cancer. Neutrophils are the most abundant white cell blood type and effectively cross physiological barriers to infiltrate solid tumors. HSCs are specific progenitor cells that will replenish all blood lineages, including neutrophils, throughout life.

'Synthetic' embryo with brain and beating heart grown from multiple stem cells

2022-09-06 - 2022-09

Researchers have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body -- a new avenue for recreating the first stages of life.

Optimization of human small intestinal organoids

2022-09-06 - 2022-09

Researchers have improved human small intestinal organoids -- miniature versions of the small intestine. This will help them to better study the functioning of the small intestine during health and disease. Specifically, the researchers managed to develop organoids that contain mature Paneth cells, which were not present in the previous human small intestinal organoids.

Hyaluranic acid, a naturally occurring compound, awakens stem cells to repair damaged muscle

2022-09-06 - 2022-09

A new study published in the journal Science reveals a unique form of cell communication that controls muscle repair. In damaged muscle, stem cells must work together with immune cells to complete the repair process, yet how these cells coordinate to ensure the efficient removal of dead tissue before making new muscle fibers has remained unknown. The scientists have now shown that a natural substance called hyaluronic acid, which is used in cosmetics and injections for osteoarthritis, is the key molecule that manages this fundamental interaction.

The chemical controlling life and death in hair follicles

2022-09-06 - 2022-09

A single chemical is a key to controlling when hair follicle cells divide, and when they die. This discovery could not only treat baldness but ultimately speed wound healing because follicles are a source of stem cells. A single chemical is a key to controlling when hair follicle cells divide, and when they die. This discovery could not only treat baldness but ultimately speed wound healing because follicles are a source of stem cells.

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The chemical controlling life and death in hair follicles

New stem cell mechanism in your gut

New patent-pending method mass-produces antitumor cells to treat blood diseases and cancer

'Synthetic' embryo with brain and beating heart grown from multiple stem cells

Optimization of human small intestinal organoids

Hyaluranic acid, a naturally occurring compound, awakens stem cells to repair damaged muscle

The chemical controlling life and death in hair follicles

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Stem Cell, Tissue Engineering and Regenerative Medicine

The chemical controlling life and death in hair follicles

New stem cell mechanism in your gut

New patent-pending method mass-produces antitumor cells to treat blood diseases and cancer

'Synthetic' embryo with brain and beating heart grown from multiple stem cells

Optimization of human small intestinal organoids

Hyaluranic acid, a naturally occurring compound, awakens stem cells to repair damaged muscle

The chemical controlling life and death in hair follicles