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Commonly used sweeteners may promote antibiotic resistance

2021-02-21 - 2021-02

Researchers in Australia have conducted a study showing that commonly used nonnutritive sweeteners can promote the spread of antibiotic-resistant genes in the intestine. The study found that the sweeteners saccharine, sucralose, aspartame, and acesulfame potassium all promoted horizontal transfer of the genes between bacteria in both environmental and clinical settings. The sweeteners accelerated the exchange of antibiotic resistance genes (ARGs) via a process called conjugation. The genes are transferred from donor to recipient bacteria, which may then go on to develop multidrug resistance, says Zhigang Yu and colleagues from The University of Queensland in St. Lucia, Brisbane.

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