Longdom Conferences

Speaker

May 31, 2021    London, UK

Webinar on Clinical Pharmacy

Pietro Mastroeni

Pietro Mastroeni

United Kingdom

Title: Medicine and Surgery Pathology

Biography:

Doctor of Medicine and Surgery at the University of Messina, Italy. 1991-94. Doctor of Philosophy (PhD), Department of Pathology and Darwin College, University of Cambridge. 2017. Doctor of Science (ScD), University of Cambridge.

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News

10 prescription drugs that don’t mix well with marijuana

2021-03-01

Marijuana contains the active cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), and interferes with drug metabolism in various ways. It can increase the levels or clearance of other drugs, as well as posing additive effects. Patients should be cautioned concerning possible cannabinoid effects. Furthermore, clinicians should try to prescribe alternative medications in the context of agents metabolized by cytochrome enzymes. Marijuana contains the active cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), and interferes with drug metabolism in various ways. It can increase the levels or clearance of other drugs, as well as posing additive effects. Patients should be cautioned concerning possible cannabinoid effects. Furthermore, clinicians should try to prescribe alternative medications in the context of agents metabolized by cytochrome enzymes. Cannabis tincture and buds Physicians should be aware of the many potential drug interactions of cannabinoids and prescription medications. Data are limited about drug-drug interactions of cannabinoids. However, in a review published in Medicines, the authors noted, “The endocannabinoids system (ECS) has garnered considerable interest as a potential therapeutic target in various carcinomas and cancer-related conditions alongside neurodegenerative diseases. Cannabinoids are implemented in several physiological processes such as appetite stimulation, energy balance, pain modulation and the control of chemotherapy-induced nausea and vomiting (CINV). However, pharmacokinetics and pharmacodynamics interactions could be perceived in drug combinations.”

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