Title: Lung cancer SBRT calculation algorithm dosimetric comparison between AAA and AcurosXB in intensity modulated radiation therapy IMRT

Abstract:

This paper's purpose is to assess the accuracy of two Algorithms, Anisotropic Analytical Algorithm (AAA) and Acuros XB (AXB) used for dose calculation in the treatment planning system Eclipse TPS (Varian Medical Systems, Palo Alto, CA). Estimating conformity (CI) and homogeneity index (HI) using 6 MV photon energy implemented in true beam linear accelerator
Material and methods: CT series of 27 non-small cell lung cancer (NSCLC) patients treated with intensity-modulated radiation therapy (IMRT) technique. Complex cases planned for stereotactic radiation body radiosurgery (SBRT) treatment, using (AAA) algorithm. Then recalculate the same plans using the Acuros XB algorithm estimating the conformity index (CI) and homogeneity index (HI) for PTV using a dose-volume histogram (DVH) for both calculation algorithms were calculated.
Results: The results of the part of the clinical study showed no significant differences for the mean dose but different noticed in conformity index for the planning target volume (PTV) for both algorithms that was between (1.45±0.55) for AAA and (2.17±0.7) for Acuros XB however the Homogeneity Index difference (0.15±0.07) for AAA and (0.1±0.08) for across XB, the maximum dose for PTV are significantly differed about 2.3% to 4.5% between them.